BIBM 2017 Workshop

BIBM2017

Welcome to BIBM Workshop

The Third Workshop on Machine Learning and Big Data Analysis for Disease Classification

Disease classification is a fundamental problem in diagnostics, genetic association, and treatment matching and personalization. Refinement of disease classification can lead to customized treatment for a complex disease. With the advances and fast development in machine learning and big data techniques, there is great progress in disease classification. Different from general classification, disease classification has a variety of problems to deal with, such as missing values, heterogeneity across different data sources, the need to factor in biological knowledge and medical knowledge of a disorder and so on.
Novel methods, statistical models and software systems are needed to address the challenges in disease classification and phenotyping. Classic methods may not achieve the analytic goal in this area. For instance, multiple imputation may be insufficient to deal with the missing values that mix obligated missing and random missing. Obligated-missing entries in a survey instrument actually encode important diagnostic information. The different data modalities used in disease classification impose additional challenges. Sophisticated transfer learning, domain adaptation, multi-task learning, multi-view data analytics might be feasible solutions. Additional caution may also be necessary in modeling temporal or spatial structures in the data, and in coping with the massive sample size and data dimensions.
There are two general lines of research for disease classification: classifying by clinical manifestations or by etiology. Clinical classifications are often useful for treatment and management. Etiologic classifications can be more useful for prevention. For both methods, phenotyping is very important to characterize and represent the disease. Up to date, there is great progress in disease data acquisition and collection as well as in the development of machine learning and bioinformatics methods, which create a dedicated subarea to health care. This workshop aims to provide a forum for academic and industrial researchers and physicians to exchange research ideas/designs and share research findings to promote the development of refined classification of complex disorders.
 

Topics

In this workshop, we solicit papers that cover but are not limited to the following topics.

  • Novel mathematical and statistical models for disease classification
  • Case studies of various diseases related to classification or phenotyping
  • Methods for effective integration of multi-scale data for disease classificationn
  • Feature selection and grouping strategies to facilitate disease classification
  • New methods to deal with missing values in study data or in electronic medical records
  • Applications of big data technologies such as deep learning, parallel and distributed computing to disease data processing
  • Quantitative disease phenotyping from electronic medical records
  • Understanding clinical symptoms from the genetic perspective
  • Evaluation of whether a disease subtype predicts differences in treatment outcomes
  • Patient similarity learning
  • QTL or eQTL with multiple quantitative sub-phenotypes of a complex disorder
  • Studies that prove the advantages of disease classification
  • The identification of novel biomarkers for a disease that helps clarify the disease definition
Submission

Your paper should be formatted to IEEE Computer Society Proceedings Manuscript Formatting Guidelines
(http://www.ieee.org/conferences_events/conferences/publishing/templates.html ).

Although we accept submissions in the form of PDF, PS, and DOC/RTF files, you are strongly encouraged to generate a PDF version for your paper submission if your paper was prepared in Word.

Please submit your paper at Machine Learning and Big Data Research for Disease Classification and Complex Phenotyping

All papers accepted for workshops will be included in the Workshop Proceedings published by the IEEE Computer Society Press, which are indexed by EI.

Presentation schedule

9:10-9:15 Predicting Sentinel Node Status in Melanoma from a Real-World EHR Dataset.
Aaron Richter and Taghi Khoshgoftaar.
9:15-9:30 Metabolic Pathway and Graph Identification of New Potential Drug Targets for Plasmodium Falciparum.
Tuan Tran and Chinwe Ekenna.
9:30-9:45 Compressive Sampling for Phenotype Classification.
Eric Brooks and Ryan Kappedal.
9:45:10:00 Markov Blanket: Efficient Strategy for Feature Subset Selection Method for High Dimensional Microarray Cancer Datasets. [video]
Kalpdrum Passi, Abdala Nour, and Chakresh Jain.
10:00-10:20 coffee break
10:20-10:35 Predicting MCI Progression with Individual Metabolic Network Based on Longitudinal FDG-PET.
Zhijun Yao, Yu Zhao, Bin Hu, Weihao Zheng, Jing Yang, Zhijie Ding, Mi Li, and Shengfu Lu.
10:35-10:50 A novel depression detection method based on pervasive EEG and EEG splitting criterion.
Jian Shen, Shengjie Zhao, Yuan Yao, Yue Wang, and Lei Feng.
10:50-11:05 Predicting ADHD using 3D Convolutional Neural Networks and fMRI Data.
Richard Platania, Shayan Shams, Kisung Lee, Seungwon Yang, and Seung-Jong Park.
11:05-11:20 Brain tumor extraction with Deep Belief Network.
Yi Ding, XueRui Li, Tian Lan, RongFeng Dong, GuangYu Shen, and ZhiGuang Qin.


Organizing Chairs

Jinbo Bi, Associate Professor of Computer Science and Engineering Department, University of Connecticut
Guoqing Chao , NIH-funded Research Associate, Department of Computer Science, University of Connecticut
Jin Lu, PhD candidate, Department of Computer Science, University of Connecticut

Program Committee

Le Lu, Staff Scientist, Department of Clinical Image Processing Service, National Institutes of Health
Sanguthevar Rajasekaran, Professor of Computer Science and Engineering, University of Connecticut
Xin Wang, Staff Scientist, Clinical Informatics Division, Phillip Global Research, Boston, MA
Shuiwang Ji, Associate Professor, Department of Electrical Engineering and Computer Science, Washington State University, WA
Jiangwen Sun, Assistant Research Professor, Department of Computer Science, University of Connecticut
Yu-Ping Wang, Associate Professor, Department of Biomedical Informatics, Tulane University

Important Dates

Oct 11, 2017: Due date for full workshop papers submission
Oct 18, 2017: Notification of paper acceptance to authors
Oct 25,  2017: Camera-ready of accepted papers
Nov 13-16 2017: Workshops

The first workshop we organized can be found in: Bioinformatics on Subtyping of Complex Phenotypes and Genetic Analysis of Phenotypic Subtypes.
The second workshop we organized can be found in :Machine Learning and Big Data Research for Disease Classification and Complex Phenotyping.